The Best Medical Strains to Grow in Minnesota

Although challenging, it's possible to grow cannabis in Minnesota's humid continental climate with hot summers and freezing winters by using the right strains and methods.

The Best Medical Strains to Grow in Minnesota

Between tornadoes and cold temperatures, weather conditions in Minnesota make it a somewhat challenging place to grow cannabis outdoors. The state receives around 30 to 40 days of thunderstorms in the summer. It also averages 27 tornadoes yearly, mainly around June to August.

Additionally, depending on where you are in the state, you can get fewer or more days in its growing season. It can have as few as 90 days in the north or 160 days in the southern region.

With all that said, it’s not impossible to grow cannabis in Minnesota. You just need the right method and strains to thrive in the state’s humid continental climate with its hot summers and freezing winters.

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Disclaimer
We are not an authority on medical matters, and this article is not medical advice. We are, instead, sharing insights from external medical and scientific research. Keep in mind responses to medical Cannabis can vary widely, and it is a good idea to consult a medical professional prior to use. Our content is no replacement for expert advice—please use it responsibly.

Harlequin

Harlequin is one of the best high-CBD cannabis strains to grow in Minnesota because of its ability to thrive in high humidity. However, if you want this sativa-dominant cultivar to flourish, consider growing it in northern Minnesota with its milder summers. Harlequin cannabis plants don’t handle excessive heat very well; they’ll dry up and eventually wither.

Harlequin Feminized Seeds

Harlequin is a sativa-dominant hybrid offering the best sativa and indica qualities. This strain delivers very effective medicinal uses with its reasonably high CBD levels.

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Harlequin is moderately difficult to grow due to its temperature and nutrient requirements. For this sativa hybrid to flourish, you must maintain a temperature of 72 to 85°F (22°C to 29°C) and ensure the plants receive plenty of nutrients. But, the effort you put into growing this strain rewards you with a considerable yield of around 14 to 17 ounces of cannabis flower per plant, with flowers boasting a high CBD content of 10 to 15%.

Read our full review of Harlequin, or buy Harlequin feminized seeds in our store, where you can also purchase marijuana fertilizers to give all the nutrients your plant needs from seedling to harvest.

Harlequin cultivar profile

Plant type 80% sativa 20% indica
THC Up to 7%
CBD 10 to 15%
Difficulty Moderate
Climate Indoors | Temperate | Continental
Plant size Tall
Vegetative stage 4 to 8 weeks
Flowering time 8 to 9 weeks
Yields 14 to 17 ounce per plant
Taste and Smell Sweet | Earthy | Mango | Spicy | Woody
Effects Uplifting | Energizing | Creativity
Terpenes Myrcene | Beta-Pinene | Caryophyllene | Geraniol | Alpha-Pinene

Strawberry Kush CBD

Strawberry Kush CBD is an Indica-dominant strain that’s suitable for growing in Minnesota. Because some parts of the state have fewer days in its growing season, many start their cannabis seeds indoors until either the marijuana plants are 1 to 2 feet tall or when the climate becomes favorable for them to be grown outdoors (typically around June).

Strawberry Kush CBD Feminized Seeds

Strawberry Kush CBD is an indica-dominant low-THC strain with high levels of CBD. It's a popular strain due to its berry taste and smell combined with a smooth high. These feminized seeds produce small, easy-to-grow plants that are perfect for beginners.

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Starting an outdoor plant indoors is only made easier if you’re growing Strawberry Kush CBD. This cultivar produces compact plants that are easier and more convenient to transfer. But don’t let this strain’s unassuming size fool you; you can yield around 16 to 23 ounces per plant.

Grow this high-yielding indica by buying Strawberry Kush CBD feminized seeds in our store, where you can also buy regular Strawberry Kush.

Strawberry Kush CBD cultivar profile

Plant type 75% indica 25% sativa
THC <1% (slight deviations may occur)
CBD up to 9%
Climate Indoors and cool climate
Plant size Compact
Vegetative stage 4 to 8 weeks
Flowering time 8 to 9 weeks
Yields 16 to 23 oz per plant
Taste and Smell Sweet | Woody
Terpenes Myrcene | Geraniol | Caryophyllene | D-Limonene | Linalool

White Rhino

This indica hybrid is one of the best marijuana strains to grow in Minnesota. White Rhino is adapted to thrive in warm and humid places, which is exactly the climate of Minnesota. Outside of Minnesota providing a preferred environment, this indica strain also delivers a generous yield.

White Rhino Feminized Seeds

White Rhino is a well-respected strain boasting of parentage from the regions of India, Afghanistan, and Brazil. Weed grown from White Rhino seeds delivers a relaxing high, perfect for those feeling stressed out.

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When grown under ideal conditions, White Rhino has a generous yield of 14 to 17 ounces per plant. An impressive amount considering how little you would need to care for its plants because of the strong genetics inherited from White Widow. 

Read our full review of White Rhino, or buy White Rhino feminized seeds in our store. Download our Harvest Guide as well to learn how to produce the most potent buds and the biggest yields.

White Rhino cultivar profile

Plant type 80% indica 20% sativa
THC Up to 20%
CBD Insignificant amounts
Difficulty Moderate
Climate Indoors | Continental
Plant size Average
Vegetative stage 4 to 8 weeks
Flowering time 8 to 10 weeks
Yields 14 to 17 oz per plant
Taste and Smell Earthy | Sweet | Woody
Effects Happy | Relaxed
Awards Cannabis Cup | Champions Cup
Terpenes Humulene | Myrcene | Beta-Pinene | L-Limonene | Caryophyllene

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Candy Kush

If you’re looking for cannabis that’s known for its sweet flavor, you’ll find that and more with Candy Kush. This indica-dominant strain isn’t just sweet. It’s also great for relaxation. It’s even popular in the medical marijuana crowd for its effects and flavor. While we can’t say for certain the benefits of THC, a study in 2022 suggests it can help with chronic pain and inflammation.

Candy Kush Feminized Seeds

Candy Kush is a marijuana strain that is perfect for enjoying at the end of the day. It's not too pungent or strong taste-wise or smell-wise, but recognizable and pleasant just the same.

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Regarding growing, Candy Kush weed plants can thrive in Minnesota’s humid climates. It also doesn’t need extra effort and attention on your part since it has a naturally high resistance to mold. On top of being an easy strain to grow, Candy Kush has a relatively short flowering time of 7 to 9 weeks, letting you harvest before the first frost.  

Grow this sweet strain by buying Candy Kush feminized seeds in our store.

Candy Kush cultivar profile

Plant type 75% indica 25% sativa
THC Up to 18%
CBD Insignificant amount
Climate Indoors | Continental
Plant size Average
Vegetative stage 4 to 8 weeks
Flowering time 7 to 9 weeks
Yields 14 to 17 oz per plant
Taste and Smell Berry | Sweet
Effects Relaxed
Terpenes D-Limonene | Carene | Myrcene | Terpineol | Humulene

Wedding Cake

Wedding Cake is an Indica-dominant strain that can grow well in Minnesota’s humid continental climate. It’s also easy to grow and doesn’t require extra effort to get a good yield. That’s why we recommend this indica hybrid for beginners and first-time growers.

Wedding Cake Feminized Seeds

Wedding Cake is known for its sweet taste and the harmony between the indica and sativa traits. If you want to chill but still remain sharp, Wedding Cake is a great choice.

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Wedding Cake’s strong genetics make it an undemanding strain to grow. This indica hybrid can produce plants resistant to diseases, mold, and other pests. The hardy plants can even handle environmental stressors such as sudden changes in weather. Add all of this to the fact that Wedding Cake plants can yield around 18 to 21 ounces per plant, and it’s clear why this cultivar is as popular as it is with growers.

Read our full review of Wedding Cake, or grow this indica hybrid yourself by buying Wedding Cake feminized and autoflower seeds in our store.

Wedding Cake cultivar profile

Plant type 70% indica 30% sativa
THC Up to 25%
CBD Insignificant amounts
Difficulty Easy
Climate Indoors | Continental
Plant size Average
Vegetative stage 4 to 8 weeks
Flowering time 8 to 10 weeks
Yields 18 to 21 oz per plant
Taste and Smell Vanilla | Sweet | Earthy | Ginger
Effects Relaxing | Energizing
Terpenes Myrcene | L-Limonene | Caryophyllene | Valencene | Linalool

Cannatonic

Cannatonic is a high CBD strain popular in the medical scene. It’s been the subject of research, like this 2018 study, which discusses the effects of medical cannabis on certain conditions. Cannatonic is also popular among growers, mainly because it can thrive both indoors and outdoors.

Cannatonic Feminized Seeds

The typical Cannatonic strain is a hybrid produced by crossing the female MK Ultra and the popular G13 Haze male. It was bred for its high CBD content (up to 12%) and high THC content, up to 6%.

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Regarding growing, Cannatonic plants require a bit more effort for them to flourish. You must monitor them constantly, and if you’re growing in a humid environment like the one in Minnesota, you must prune them to encourage better airflow and prevent mold growth. This is because Cannatonic plants, although resistant to most pests, may suffer from mold issues.

Grow Cannatonic by buying Cannatonic feminized seeds in our store, where you can also buy plant protectors to ensure your cannabis plants are safe from harmful pests and diseases.

Cannatonic cultivar profile

Plant type 50% indica 50% sativa
THC Up to 6%
CBD Up to 12%
Difficulty Easy
Climate Indoors | Continental
Plant size Tall
Vegetative stage 4 to 8 weeks
Flowering time 10 to 11 weeks
Yields 14 to 18 oz per plant
Taste and Smell Herbal | Pine | Peppery
Effects Relaxing | Happy | Uplifted
Terpenes Linalool | Beta-Pinene | Valencene | D-Limonene | Caryophyllene

Blue Haze

Blue Haze is a Sativa-dominant strain adapted to growing in humid continental climates like the one Minnesota offers. It’s also a great indoor plant if you need to start your grow inside before transferring the plants outdoors when the climate becomes favorable for them.

Blue Haze Feminized Seeds

Blue Haze seeds will rock your world. You'll find yourself experiencing a euphoria much like that created by the scenic green fields and country views in a scene of a Michelangelo painting.

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When growing Blue Haze cannabis, you must put in a little more work to ensure you get the highest yield possible. But the effort you put into maintaining the ideal growing conditions for your marijuana plant is worth it, as it has a considerable yield of 17 ounces per plant, with flowers boasting a THC content of up to 20%.

Read our full review of Blue Haze, or buy Blue Haze feminized seeds in our store. Download our Plant Care Guide as well to learn how to best treat your plants.

Blue Haze cultivar profile

Plant type 20% indica 80% sativa
THC Up to 20%
CBD Insignificant amount
Difficulty Moderate
Climate Indoors | Mediterranean | Continental
Plant size Average
Vegetative stage 4 to 8 weeks
Flowering time 10 weeks
Yields 14 to 17 oz per plant
Taste and Smell Blueberry | Strawberry
Effects Euphoric
Terpenes Caryophyllene | Beta-Pinene | Linalool | Ocimene | Carene

Gold Leaf

Robert Bergman’s blend, Gold Leaf, is an indica hybrid known for its consistent and considerable yields. So, if you’re looking for a high-yielding marijuana strain to grow in Minnesota, look no further.

Gold Leaf Feminized Seeds

When Robert Bergman created the Gold Leaf Strain, he combined multiple plants to produce a refined, sativa-style height plant with indica traits users love.

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You won’t find it hard to cultivate Gold Leaf since it has adapted to grow in almost any environment, including Minnesota’s humid continental climate. Under ideal growing conditions, this hybrid strain can yield 16 to 23 ounces per plant, with flowers containing a THC content of up to 21%. You will still have to start your grow indoors, but that won’t be much of a concern since Gold Leaf also grows well as an indoor plant.

Cultivate Gold Leaf by buying Gold Leaf feminized and autoflower seeds in our store.

Gold Leaf cultivar profile

Plant type 60% indica 40% sativa
THC Up to 21%
CBD Insignificant amounts
Difficulty Moderate
Climate Indoors | Steppe | Mediterranean |and Continental
Plant size Tall
Vegetative stage 4 to 8 weeks
Flowering time 9 weeks
Yields 16 to 23 oz per plant
Taste and Smell Earthy | Herbal | Pungent | Spicy | Sweet
Effects Euphoric | Happy | Relaxed | Uplifted
Terpenes Alpha-Pinene | Myrcene | Caryophyllene | D-Limonene | Valencene

Afghan

Afghan is a pure indica strain originating from the Hindu Kush Mountain Range, which has a harsh climate with hot, dry summers and cold, wet winners. The environmental stressors of the mountain range made Afghan a hardy cannabis plant that can flourish in just about any climate, including Minnesota’s warm and humid growing conditions.

Afghan Feminized Seeds

Afghan is a very popular indica heritage strain that delivers a heavy-bodied high. Afghan seeds grow large, fragrant buds known for their happy, relaxed effect.

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When grown under ideal conditions, Afghan cannabis can yield 14 to 21 ounces per plant. And the best part about this indica strain is that it doesn’t need a lot of extra effort for you to get a considerable yield from its plants. It has been developed and redeveloped over the centuries until it only produced hardy plants with strong genetics.

Grow Afghan cannabis by buying Afghan feminized and autoflower seeds in our store.

Afghan cultivar profile

Plant type 100% indica
THC Up to 20%
CBD Insignificant amounts
Difficulty Easy
Climate Indoors | Continental | Mold Resistant
Plant size Average
Vegetative stage 4 to 8 weeks
Flowering time 8 to 10 weeks
Yields 14 to 21 oz per plant
Taste and Smell Earthy | Herbal | Pungent | Spicy | Sweet | Woody
Effects Euphoric | Happy | Hungry | Relaxed | Sleepy
Terpenes Humulene | Alpha Pinene | Terpinolene | Myrcene | Carene

Black Widow

Black Widow is a sativa hybrid strain developed by Shantibaba, who made the original White Widow for Green House Seeds by crossing a Brazilian sativa with a South Indian indica hybrid. At first, he named it White Widow since it used the same cannabis strains to make it. However, since GHS was still selling their seeds using the name White Widow, he had to rename his cultivar Black Widow.

Black Widow Feminized Seeds

Black widow is a very potent strain of Cannabis with between 15% to 28% THC contents. It comes with some effective medicinal properties while offering a decent level of CBD.

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Despite being named after a highly venomous spider, Black Widow is anything but dangerous. Instead, it’s a great sativa hybrid to smoke when you’re ready to unwind or need something to help you relax. And with its THC content of up to 28%, you’re guaranteed to feel deeply relaxed after a few tokes from this potent strain.

Just like its effects, growing Black Widow is relaxing. Although not entirely effortless, growing this marijuana won’t require too much of your attention. This is because its hardy plants have a high resistance to most pests and diseases. It’s also mold-resistant and can flourish in Minnesota’s humid continental climates.

Read our full review of Black Widow, or buy Black Widow feminized seeds in our store.

Black Widow cultivar profile

Plant type 40% indica 60% sativa
THC Up to 28%
CBD Insignificant amounts
Difficulty Easy
Climate Indoors | Steppe | Mediterranean | Continental | Mold Resistant
Plant size Average
Vegetative stage 4 to 8 weeks
Flowering time 8 to 10 weeks
Yields 11 to 16 oz per plant
Taste and Smell Berry | Earthy | Woody
Effects Relaxed
Terpenes Beta-Pinene | D-Limonene | Terpinolene | Ocimene | Caryophyllene

Conclusion

Growing cannabis as a hobby or a necessity can be easy when you know what you are doing. If you want to learn how to cultivate cannabis like a pro, download Robert’s Grow Bible, a free 70-page grow guide to growing the best cannabis.